This study aims to determine how the influence and description of the level of job stress, occupational safety, and health (OSH) on employees' quality of work life at the post office of Central Cimahi. The method used in this research is descriptive and causal quantitative methods. Sample used for this research is simple random sampling, with a sample size of 20 people. The data analysis technique of this research is descriptive analysis and multiple regression analysis.
Based on the results of simultaneous hypothesis testing, it shows that job stress, occupational safety, and health have a positive and significant effect on the quality of work life of the Cimahi Post Office employees. While partially the job stress variable (X1) has a significant effect on the Quality of Work Life (Y), while for the Occupational Health and Safety (X2) variable there is no significant effect on the Quality of Work Life (Y) partially. The result of the calculation of the coefficient of determination in this study is 69.4%, indicating that job stress, occupational safety and health affect the quality of work life of employees while other factors influence the remaining 30.6%.