In Malaysia, Swiftlet nests have become one of the major agricultural commodity exports. There are many entrepreneurs who face problems in the swiftlet nest farming industry so they cause a lot of losses. The aim of the research is to find the weightage in start-up business factors in edible bird nest ranching industry. A total of eight participants among academic, veterinary and entrepreneurs will be chosen for interviewing to find the weightage of the start-up business factors. The findings showed the weightage of the start-up business factors can be found in the interview. By using the weightage of the start-up business, the system of start-up business factors in edible bird nest ranching industry will be developed.