This research aims to design a system that supports innovation towards the value of efficiency in the production process by achieving a better documentation and dissemination of knowledge to all employees at CV. XYZ Leathercraft. Knowledge Management System (KMS) is a part of development and maintenance process in a company. The factors of this research are people, process, and technology. Maynard Operation Sequence Technique (MOST) is required to implement Knowledge Management System towards the value of efficiency in the production process as a work measurement technique that concentrates on the movement of objects. This strategy is designed to obtain the features of application that are relevant to the situation at CV. XYZ Leathercraft. The result of this research shows that the implementation of Knowledge Management System has features that consist of discussion forum, knowledge sharing, library, event, record of production process, and marketing map.