The sustainability of the supply chain has emerged as a major concern that is getting a lot of attention nowadays. and supplier selection can be optimizing the overall value of the supply chain in maintaining the company’s profitability and sustainability. In the healthcare section, greater attention to maximizing revenue and less attention is paid to sustainability in the organization. Furthermore, the effect of the important weight of sub-criteria on the Fuzzy TOPSIS approach was not attempted in the field of choosing a hospital supplier. To address this problem, this research conducts a new Fuzzy TOPSIS approach to examine the considerable influence of sub-criteria for sustainable hospital supplier problems, which main criteria and their sub-criteria of sustainability dimensions in this hospital setting from the decision-makers ‘argument. Based on an extensive review of relevant literature and the perspectives of decision-makers; there are ten criteria, and twenty-four of their sub-criteria confirmed the validity of evaluating the three hospital supplies. A sensitivity analysis was also performed to evaluate the suggested framework by implying a change in the different criteria and decision-makers. As the results show that suppler one is the best sustainable supplier in most scenarios. Alternatively, if the hospital supplier selection process is considered only economic criteria, aiming to maximize revenue, this issue suggested supplier two is the best performance ranking. This research suggested frameworks can help hospital managers make decisions on potential suppliers within the sustainability dimension of their supply chain operation and practices.