Edible film packaging is a relatively new food preservation technique. Many research has been carried out and have shown the extended shelf life and improved the quality of food products. One of the safest edible films for food was made from gelatin. In this study, we have made the gelatin from the wastes of catfish bone demineralization was carried out using 4% HCl for 5 hours, until it reached a pH of 5 extracted using 70C distilled water for 5 hours. The turmeric extract obtained from the maceration of 96% methanol for 2 days, the filtrate then evaporated and impregnated into gelatin as a specific antimicrobial for Escherichia coli, a gram-positive bacteria with the ratio of ossein catfish bone: distilled water: turmeric extract is (10:50:0); (10:50:5); and (10:50:10) % w/w. The films were applied to apples. The efficacy of the existing films against Escherichia coli bacteria for the coming 20 days was studied using the modified disc method. The acceptance test of film products was carried out using the organoleptic method