Catla catla and Channa striata fish samples were collected from various sites of Kurnool district of Andhra Pradesh. This comparative study examines the ectoparasitic and endoparasitic infestations in two freshwater fish species Catla catla and Channa striata. Both species common in South Asian freshwater ecosystems differ in their feeding habits and ecological niches which influence their susceptibility to parasitic infections. The study highlights differences in parasite prevalence and type with Catla catla fishes showing higher ectoparasitic loads, especially on the gills and Channa striata infections due to its predatory diet. This comparison underscores the role of feeding behavior and habitat in shaping parasitic communities in freshwater fish species.