With the evolution of global production through Industry 4.0, the incorporation of digital technology into quality management systems, referred to as Quality 4.0, has become crucial for improving competitiveness. However, research on Quality 4.0 implementation in developing countries, particularly in Indonesia, remains limited. This study conducts an exploratory investigation of global trends in Quality 4.0 by analyzing 50 academic papers, identifying key themes such as the use of AI, IoT, and big data in quality control. The results highlight a significant gap in research related to developing economies, including Indonesia, where unique challenges like limited digital infrastructure, workforce skills, and financial constraints hinder the adoption of Quality 4.0. Based on these findings, this paper proposes a research agenda and conceptual framework tailored to the specific needs of Indonesian manufacturing firms, focusing on improving technological readiness, upskilling the workforce, and fostering government support to facilitate the transition to Quality 4.0.