For the past decades, the supply chain network has been significantly influenced by several major factors. Standing out of those is global warming which causes radical changes in traditional supply chain network. Therefore, environmental vulnerability with legality and economic benefits has made supply chain management to be as an important objective for companies and governments. Sustainability must be built-in supply chain network design (SCND), by striking the right balance between cost-cutting and environmental preservation. The goal of this paper is to develop a green closed–loop supply chain (G-CLSC) network by first, evaluating supplier selection with Multi-criteria decision-making (MCDM). Subsequently, a bi – objective Mixed-Integer Linear Programming (MILP) model is presented for facilities allocating and consolidate closed-loop flow, with two objectives: minimizing operating cost and minimizing CO2 emission. The model is testified by implying on the case of a Vietnamese plastic injection enterprise consisting of facilities spreading all over the country. The simulated result demonstrates the efficiency and validity of the proposed solution model. All possible solutions are measured thoroughly to identify the optimal design for prior environment protection. Ultimately, the solution model finalizes with a forward and a reverse supply chain network.