Low Back Pain (LBP) is a common global musculoskeletal problem and has been the leading cause of disability among public transport drivers. The present design of motorized tricycles in the Philippines focuses more on aesthetics, neglecting the drivers' comfort, safety, and well-being. It is a concern that drivers' quality of life and transportation needs to be improved. The study aims to identify the ergonomic risk factors of LBP among tricycle drivers in the vicinity of the University of Santo Tomas-Manila. Moreover, this study will provide improvements and recommendations to prevent low back pain and provide convenience and comfort. The data was gathered through a questionnaire and analyzed through Ordinal Logistic Regression using SPSS statistical software. Further assessment was made on the significant factors affecting the lower back of the tricycle drivers. The results showed that the age, sitting height, hip breadth measurements, and environmental conditions such as type of traffic and motor vibration significantly contributed to the LBP of the tricycle drivers. The findings implied that tricycle drivers are at risk of developing reduced well-being and comfort. A lifestyle modification for tricycle drivers and the establishment of procedures aimed to address the LBP were recommended.