This study aimed to determine and analyze the influence of Human Resource (HR) competence and compensation on job satisfaction through excellent service at Lagaligo Hospital I, East Luwu Regency. This research was conducted at Lagaligo Hospital I, East Luwu Regency, using a causality design with a quantitative approach. The population of this study were all employees at Lagaligo Hospital I, East Luwu Regency, as many as 327 people. Sampling using simple random sampling technique, the final sample used was 120 people. Data were collected through observation, questionnaires, interviews, and documentation—data analysis using path analysis. The results showed that the provision of compensation is essential in increasing job satisfaction, which is indicated by the hospital management's ability to manage fair and proportional compensation. In addition, the competence of human resources is also an essential factor in increasing the level of employee satisfaction. Excellent service also influences job satisfaction where employees and health workers carry out their assigned tasks prioritize transparency and participation, meaning that the services they provide can provide satisfaction for themselves and patients as consumers. For an indirect effect, the competence of human resources can improve excellent service and then achieve job satisfaction.