This research aims to analyze and find out the relationship between fire knowledge and training through the readiness of Service Officers and Health Support officers to officers' performance in handling fires that may occur in BBKPM Makassar, especially in the room where they work. The research was carried out at the Makassar Public Lung Health Center (BBKPM) from December 21, 2021, to January 29, 2021, with 106 respondents as the sample number. Sampling in this study used questionnaires as primary data obtained through the results of questionnaire answers conducted by each respondent. The method of analysis taken by researchers is Path Analysis or Path Analysis because researchers want to ensure the influence of Knowledge and Training on Officer Performance in Fire Handling through Officer Readiness at the Makassar Public Lung Health Center (BBKPM). This type of research method is Quantitative with the research design used, namely Survey Research, and uses a Cross-Sectional approach. The results are seven hypotheses in this study, where positive and significant results can prove the validity of the hypothesis. However, the level of significance of Knowledge and training on Officer Readiness and Knowledge of performance is higher when compared to training on officer performance and officer readiness to performance.