DKI Jakarta often experiences flood disasters when the rainy season hits. The floods caused a number of residents to be affected so that residents needed to evacuate to safer places, such as refugee posts. Citizens who secure themselves at the post certainly need some necessary needs such as humanitarian logistics goods. Humanitarian logistics goods need to be distributed quickly and precisely so that optimal distribution lines are needed. This research aims to find out the route of distribution of humanitarian logistics goods that occur in Jakarta, especially East Jakarta. This problem is solved by using the Saving Matrix method with the Nearest Neighbor and Nearest Insertion method as a route sorting method. The results of the route determination are known that the optimal distribution path is obtained from the first alternative using the Nearest Neighbor method with a total distance of 130.25 m.