According to a study, with the new arrangements of work setup, such as working from home due to COVID-19, there are benefits as well as challenges that need to be addressed, including but not limited to environmental workplace suitability and possibly obesity. The Department of Health and several related organizations stated that “among Filipino adolescents, overweight has tripled in the last 15 years.” Additionally, there is a gradually increasing trend, with 3 out of 10 Filipino adults classified as overweight and obese. Furthermore, there are policies from work-from-home setups that are intermittently imposed for long periods, which affect the behavior of an adult, such as physical activity and eating habits. This study shall be a pathway that encompasses the Human Resources department and industrial engineers to develop a way to manage and alleviate obesity complications in the workplace. The study aimed to determine the factors that affect BMI and predict what variable significantly influences it. The researchers focused on employees who are in a work-from-home setup and are still experiencing working from home in the Philippines. The proponents gathered their lifestyle and environmental factors through a survey questionnaire. The researchers utilized SPSS to analyze the data. The data was analyzed by using regression analysis, specifically Multiple Linear Regression. The predictive model that the software created was shown to be significant. The two significant independent values, specifically, Fast food Consumption and Work Stress, were determined by looking at the significant values in the coefficients table.  The data and model satisfied the multiple linear regression assumptions; thus, the model is valid. Given the results, the proponents recommend that the company, especially HR employee relations officers, implement policies and create programs that promote eating habits as well as alleviate work stress in the workplace.