With the fast rise of e-sports, gaming setups have been a new field of discovering which standards fit the comfort of online gamers. This led to the interest in conducting this study to determine the effects of workstation designs on online gamers and the body discomfort they encounter. The researchers used data from 50 online gamers respondents in National Capital Region in the Philippines, which was analyzed using correlation analysis and a chi-square test. RULA was also used to evaluate the MSD risk of respondents. Results have shown that using a side chair, gaming keyboard, mechanical keyboard, and laptop keyboard significantly differs in a person's body posture and that most online gamers feel discomfort in their mid-back due to their body posture. The desk, chair, keyboard, and mouse are significantly associated with a person's body discomfort. The findings indicate that different workstation designs affect the body discomfort online gamers encounter.